Q) Describe the roles of NAD and NADP in cells
Main points | |
Key idea: | What are NAD and NADP |
· Both are coenz + e acceptors · When reduced (as NADH and NADPH), both temporarily store energized e + H+ & before transferring them to electron transfer chain (ETC) | |
Key idea: | Role of NADP during photosynthesis (light dep + indept rx) |
· Found in stroma of chloroplast, plant cells · NADP as final e acceptor of ETC (at thylakoid membr) (combines w e & H+ to NADPH) during light dep rx · NADPH produced needed for light indep rx (Calvin cycle) · Ref to reduction of glycerate-3-phosphate to triose phosphate (TP) + during which NADP is regenerated for light dep rx · Some TP combine to form glucose phosphates, & eventually produce starch, fats, proteins + others to regenerate ribulose bisphosphate (RuBP) for carbon fixation | |
Key idea: | Role of NAD during cellular respiration |
· Found in mitochondrial matrix + cytoplasm of cells · NAD reduced during glycolysis, link reaction & Krebs cycle by dehydrogenation rx · NADH donates its e to ETC (embedded at inner mitochondrial membr) · During oxidative phosphorylation, transfer of e throu ETC, down energy gradient, forms H+ conc gradient, & eventually syn of ATP · Ref to 3 ATP / NADH · NAD is regenerated for glycolysis, link reaction & Krebs cycle to continue, hence ATP syn via substrate-level phosphorylation + oxidative phosphorylation | |
Comments: (i) Visualize the answer with the aid of a labelled diagram. (ii) Verbalize the answer + write down the main points w/o referring to the answer (use abbreviations) (iii) Read again within the next 24h & once more within 72h (do not spend more than 10min) | |
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