Q) Describe the structural features of collagen
Main points | |
Key idea: | What is collagen + bonds + building blocks |
· A fibrous protein made up of aa · joined by peptide bonds · Each polypeptide chain made up of mainly glycine, proline & hydroxyproline · Ref to polypep having a kinked helical shape (as glycines are small compared to larger sized proline & hydroxyproline) | |
Key idea: | Organization of collagen |
· 3 of such polypep coil around each other (by H bonds), to form the triple helical struc of repeating unit - tropocollagen · Ref to covalent cross-linkages b/w adjacent tropocollagens, to form collagen fibril · Ref to staggered arrangement of tropocollagens - no weak point a/x collagen fibril · Collagen fibrils bundle to form collagen fibres | |
Comments: (i) Visualize the answer with the aid of a labelled diagram. (ii) Verbalize the answer + write down the main points w/o referring to the answer (use abbreviations) (iii) Read again within the next 24h & once more within 72h (do not spend more than 10min) (iv) You should be able to explain the structural adaptation of collagen to its function and compare between collagen and cellulose | |
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