Sunday, November 6, 2011

Topic Biomolecule (Lipid) Essay - Main Points!


Q) Describe the main differences in the molecular structure of triglycerides and phospholipids
Main points
Key idea:
Components and bonds
Triglyceride
· Formed fr 1 glycerol + 3 fatty acids (FA) via condensation rx
· Via formation of 3 ester linkages
· Ref to each ester linkage due to
· Ref to hydroxyl (OH) gp of glycerol reacts w carboxyl (COOH) gp of FA
Phospholipid
· Formed fr 1 glycerol + 2 FA + 1 phosphoric acid via condensation rx
· Via formation of 2 ester linkages + 1 phosphoester linkage, respectively
Key idea:
Type of lipid
 Triglyceride
· Simple lipid
Phospholipid
· Complex lipid
Key idea:
Amphiphathic property of phospholipid
Phospholipid
· Phosphate often bonded to a nitrogen-containing organic gp (e.g. choline)
· Hydrophilic polar head comprises of glycerol residue, phosphate & organic base; can ionize in water
· 2 hydrophobic non-polar hydrocarbon chains of FA residues
· Ref to both hydrophilic + hydrophobic regions of mol gives rise to amphipathic property (absent in triglyceride)
Comments:
(i) Visualize the answer with the aid of a labelled diagram (showing the formation of triglyceride and phospholipid)
(ii) Verbalize the answer + write down the main points w/o referring to the answer (use abbreviations)
(iii) Read again within the next 24h & once more within 72h (do not spend more than 10min)

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