Tuesday, October 4, 2011

Topic Nuclear Division Essay - Main Points!

Q) Explain how mitosis give rise to genetically identical cells
Main points
Key idea:
What is mitosis
· A process in which a nucleus divides to produce 2 daughter nuclei, each containing the same no. of chrom as original nucleus
· Consist of prophase, metaphase, anaphase and telophase
Key idea:
Duplication of chromosome (DNA) during S phase
· Mitosis is preceded by interphase
· During S phase ( interphase), DNA replicates in a semi-conservative manner - each chrom is duplicated
· Forms a double struc consisting of two genetically identical sis chromatids joined at centromere
· Each chromosome condense during prophase (of mitosis)
Key idea:
Equal distribution of chrom in daughter nuclei due to metaphase & subsequent anaphase
· Arrangement of chrom on the equator of cell during metaphase ensures equal distribution of chrom b/w daughter cells
· Reason : During anaphase, centromere of each chrom divides, 2 genetically identical sis chromatids of each chrom separates to opp poles of cell
· Ref to migration of sis chromatids aided by shortening of pole-to-centromere spindle fibres + when separated, each sis chromatid is now a new chrom*(iv)
Key idea:
Formation of genetically identical daughter cells by subsequent cytokinesis
· By end of telophase, both daughter nuclei at opp poles will each consists of a set of genetically identical chromosomes
· By end of cytoplasmic division (i.e. cytokinesis), genetically identical (daughter) cells are formed 
Comments:
(i) Visualize the answer with the aid of a labelled diagram.
(ii) Verbalize the answer + write down the main points w/o referring to the answer (use abbreviations)
(iii) Read again within the next 24h & once more within 72h (do not spend more than 10min)
(iv) *At this point (anaphase), the no. of chrom in the cell has doubled

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