Q) Discuss the goals of the Human Genome Project (HGP)
Main points | |
Key idea: | Create detailed physical map of the human genome |
· To determine seq of 3 billion chemical bps that make up human DNA · based on DNA fr 6 to 10 anonymous | |
Key idea: | Databases + informatics for data analsyis |
· To store DNA seq info in publicly-accessible databases · To improve bioinformatics tools, for identifying ~30,000 genes + their locations in human DNA, gene regulation, protein properties, 3D struc, etc · E.g. of identifying genes - scan DNA seq (e.g. promoter elements typically assoc w genes, conserved intron seq, coding regions) · Also determine genetic basis of diseases, to study seq variations related to disease | |
Key idea: | Address other issues |
· Ref to ethical, legal, and social issues arising fr project | |
Comments: (i) Verbalize the answer + write down the main points w/o referring to the answer (use abbreviations) (ii) Read again within the next 24h & once more within 72h (do not spend more than 10min) | |
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