Sunday, September 25, 2011

Topic Evolution and Diversity Essay - Main Points!


Q) Explain the benefits of the molecular classification of organisms
Main points
Key idea:
Basis of using molecular methods to classify organisms
· All organisms can be classified throu this method since all known life is based on nucleic acids
· Involves comparing nucleotide bases b/w organisms to determine their evolutionary relatedness
· Closely related organisms share similar base sequences as compared to distantly related organisms
Key idea:
Adv 1: Almost limitless set of characters for analysis
· Base sequences – each nucleotide base at each position of chrom can be considered as a character
· Almost limitless no. of characters since genome of organisms consists of millions of nucleotides
· Type of molecular data often used - DNA sequence of a gene that change (mutate) at a fairly constant rate + mutation that is selectively neutral
Key idea:
Adv 2: Molecular data is quantifiable and accessible  
· Data can be submitted or retrieved from an online database to compute the probable relatedness of two organisms in a quantitative manner
Key idea:
Adv 3: Molecular data is objective (unambiguous)
· Avoids pitfalls of convergent evolution or subjective nature of distinguishing morphological struc
Key idea:
Adv 4: Differences in molecular data 
· Differences in mol data can be used to (i) accurately determine degree of relatedness b/w organisms with very different phenotypes (ii) classify organisms even if their phenotypes are highly similar
Key idea:
Adv 5: Applicable even for extinct / non-living organisms
· Can classify organisms even if they are no longer living since DNA is highly stable so can be retrieved from living or dead cells
· Once sequenced, data can be stored indefinitely (via electronic database)
Comments:
(i) Verbalize the answer + write down the main points w/o referring to the answer (use abbreviations)
(ii) Read again within the next 24h & once more within 72h (do not spend more than 10min)
(iii) Assumption for Adv 5 - DNA is not degraded. Given the right conditions and the stability of DNA, this molecular method is especially useful for studying extinct species.
(iv) I’ll modified the last point (Adv 4 & 5) slightly to make them easier to understand (hopefully !)

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