Q) Describe the formation of peptide bond between two amino acids
| Main points | |
| Key idea: | Structural features of an amino acid |
| · Components: 1 amine group (-NH2) & 1 carboxyl group (-COOH) attached to a central (α-carbon atom) · where α-carbon also joined to 1 H atom & 1 variable R gp/side chain · Ref to properties of aa determined by R gp | |
| Key idea: | Formation of dipeptide |
| · Location: Formation of a peptide bond b/w 2 aa at ribosome, in cytoplasm of cell, catalyzed by peptidyl transferase (of large ribosomal subunit) · Process: Condensation rx, -NH2 gp of 1 aa reacts w -COOH gp of other aa, with 1 H2O mol lost | |
| Comments: (i) Visualize the answer with the aid of a labelled diagram (to show the formation of a dipeptide) (ii) Verbalize the answer + write down the main points w/o referring to the answer (use abbreviations) (iii) Read again within the next 24h & once more within 72h (do not spend more than 10min) | |
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